Department of Chemistry
University of South Florida
4202 E. Fowler Avenue, CHE 205A
Tampa, FL 33620-5250
Office: (813) 974-7438, NES 230
Lab: (813) 974-9012, NES 332
Email: jantilla@cas.usf.edu
B.S., Northern Michigan University, 1995
Ph.D., University of Chicago, 2000
Postdoctoral Fellow (NIH-NCI), Massachusetts Institute of Technology, 2000-2003
Chiral Organocatalysis, Metal-Catalysis, New Stereoselective Reaction Methodology, Drug Discovery.
We have now made significant inroads into a new area of organocatalysis that utilize chiral Phosphoric acids in a number of interesting synthetic transformations. We have published the first examples in the literature where chiral N,N- or N,O-aminals can be formed in a catalytic enantioselective manner. This new approach to catalysis should allow for the general synthesis of highly desired chiral heterocycles. Recently, we have begun collaboration with the medical center to develop drugs for post-stroke treatment. These potential drugs are based upon a promising lead structure with a guanidine core. We are currently developing synthetic routes to synthetic guanidine analogues.
Michelle Cortes-Salva, Gajendrasingh Ingle, Pankaj Jain, Young Ran Ji, Matthew Kaplan, Shawn E. Larson, Tao Liang
Dr. Ying Dou, Dr. Changwon Kang,Dr. Guilong Li, Dr. Zuhui Zhang, Dr. Wenhua Zheng
Dr. Suoqin Zhang
Title: Brønsted Acid-Catalyzed Asymmetric Additions to Imines (Sole PI)
Agency: PRF $ 40,000.00 1/1/07-8/31/09
Type: Type G Starter (PRF# 45899-G1) (Sole PI)
Title: The development of New Stereoselective Organocatalytic Processes (Sole PI)
Agency: NIH $ 1,318,849.00 9/1/07-8/31/12
Type: R01 (GM082935) (Sole PI)
Title: Chiral Phosphoric Acid-Catalyzed Reaction Methodology and Synthetic Applications
Agency: NSF $ 550,000 4/1/08-3/31/13
Type: CAREER (CHE-0847108) (Sole PI)
Title: Novel Neuronal Nicotinic Receptor Modulators for the Treatment of Ataxia
Agency: FCoE-BITT $ 70,000 5/1/09-4/30/10
Type: Internal Grant (Co-PI on this seed grant)
Title: Synthesis and Screening of Sigma Ligands for Stroke Treatment at Delayed Time Points
Agency: James and Ester King Biomedical Research $ 999,360 7/1/09-6/30/11
Type: Florida Department of Health State Grant (Co-PI on this Team Science Grant)
Title: Synthesis and Screening of Sigma Receptor Ligands for Stroke Therapy at Delayed Time Points
Agency: FCoE-BITT (Co-PI on this seed grant) $ 75,000 2/1/08-1/31/09
Type: Internal Grant
| REF | PRX CRS | SEC | Course Title | CR | Day | Time | Bldg | Room |
|---|---|---|---|---|---|---|---|---|
| 80159 | CHM 2210 | 001 | Organic Chemistry I M 7:35pm-9:45pm, scheduled exam time. You can register in organic lecture w/out the lab, but not |
3 | MWF T M |
10:45am-11:35am 8:00am-8:50am 7:35pm-9:45pm |
BSF CHE ULH |
100 303 101 |
| 80160 | CHM 2210 | 002 | Organic Chemistry I M 7:35pm-9:45pm, scheduled exam time. You can register in organic lecture w/out the lab, but not |
3 | MWF T M |
10:45am-11:35am 9:30am-10:20am 7:35pm-9:45pm |
BSF CHE ULH |
100 101A 101 |
| 80161 | CHM 2210 | 003 | Organic Chemistry I M 7:35pm-9:45pm, scheduled exam time. You can register in organic lecture w/out the lab, but not |
3 | MWF T M |
10:45am-11:35am 11:00am-11:50am 7:35pm-9:45pm |
BSF CHE ULH |
100 302 101 |
| 80162 | CHM 2210 | 004 | Organic Chemistry I M 7:35pm-9:45pm, scheduled exam time. You can register in organic lecture w/out the lab, but not |
3 | MWF T M |
10:45am-11:35am 12:30pm-1:20pm 7:35pm-9:45pm |
BSF PHY ULH |
100 118 101 |
| 80163 | CHM 2210 | 005 | Organic Chemistry I M 7:35pm-9:45pm, scheduled exam time. You can register in organic lecture w/out the lab, but not |
3 | MWF T M |
10:45am-11:35am 2:00pm-2:50pm 7:35pm-9:45pm |
BSF SOC ULH |
100 160 101 |
| 80164 | CHM 2210 | 006 | Organic Chemistry I M 7:35pm-9:45pm, scheduled exam time. You can register in organic lecture w/out the lab, but not |
3 | MWF T M |
10:45am-11:35am 9:30am-10:20am 7:35pm-9:45pm |
BSF CPR EDU |
100 481 115 |
| 80165 | CHM 2210 | 007 | Organic Chemistry I M 7:35pm-9:45pm, scheduled exam time. You can register in organic lecture w/out the lab, but not |
3 | MWF T M |
10:45am-11:35am 12:30pm-1:20pm 7:35pm-9:45pm |
BSF CHE EDU |
100 217 115 |