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Kirpal  Bisht

Kirpal Bisht

Kirpal Bisht
Associate Professor


Office: NES 408B
Phone: 813/974-0350
Lab: NES 407



Ph.D., University of Delhi, 1995


Efficient and environmentally friendly synthetic routes towards synthesis of polymers for biodegradable applications; Stereo controlled synthesis/modification of molecules that serve as precursors to biologically active molecule, i.e., unnatural amino acids, sugars, etc.; Regio and stereo-selective synthesis of multi-arm dendrimers by chemo/enzymatic routes.

Current Funding

View our currently funded projects here.

Graduate Students

Ali Husain, Arthur Maknenko

Current Courses

RefCourseSecCourse TitleCRDayTimeLocation
94242CHM 4230001Spect. Anal. of Org. Compds


ISA 3048

80167CHM 4970004Undergraduate Research
Requires Instructor Approval S-U Only


94241CHM 6235001Spect. Anal. of Organic Compds


ISA 3048

80171CHM 6936001Chemistry Colloquium
With emphasis on Drug Discoveries S-U Only


NES 104

90927CHM 6971004Thesis: Master's
S-U Only


84810CHM 6973004Directed Research
S-U Only


80188CHM 7820004Directed Research
S-U Only


84824CHM 7980004Dissertation: Doctoral
Adm To Doc Candidacy Req, S-U Only


Recent Publications


  1. Cyclic Ester Ring-Opened Oligomers and Methods of Preparation. Richard A. Gross, Kirpal S. Bisht, David L. Kaplan, Graham Swift and Fang Deng. US Patent Patent # 5,981,743 issued November 9, 1999.
  2. Treatment of Cancer with Chemically-modified Sophorolipids. Richard A. Gross, Kirpal S. Bisht, Carmen Scholtz, Sashi Mehta, Vladimir Guilmanov, and Robert Nicolosi. US Patent Application 60/092,446 filed on July 10, 1998.
  3. Patent Application: "Farnesylamine derivatives and method of use" Ravi Kothapalli and Kirpal Bisht. US Patent Application 60/917,861 filed on May 14, 2007.


  1. Under Preparation / Submitted: A novel approach to manipulation of the cavity size in cavitands. Sumedh Parulkar, Kirankirti Muppala, Frank R Fronczek, and Kirpal S. Bisht. Journal of Organic Chemistry. Submission planned June 2007.
  2. Synthesis of Resorcin[4]arene Cavitands by Ring Closing Metathesis. Sumedh N. Parulekar, Kirankirti Muppalla, Frank R. Fronczek and Kirpal S. Bisht. Chemical Communications, 2007, DOI:10.1039/ B712981E (in press).
  3. Novel synthesis and polymerization of protected dihydroxy 7-member cyclic carbonate. Ruizhi Wu and Kirpal S Bisht. Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), 2007, 48(1), 240-241.
  4. Pd(0) catalyzed intramolecular alkylation: Stereoselective synthesis of furan and isoxazoline-2-oxide analogs. Pasha Khan, Ruizhi Wu, and Kirpal Bisht, Tetrahedron, 2007, 63, 1116-1126.
  5. Synthesis of glycolipid analogs via highly regioselective macrolactonization catalyzed by lipase. Kirpal S. Bisht, Surbhi Bhatt, and Kirankirti Muppalla Tetrahedron Letters, 2006, 47, 8645-8649.
  6. Enantioenriched substituted polycaprolactones by enzyme catalysis. In Polymer Biocatalysis and Biomaterials. Kirpal S. Bisht; Leelakrishna Kondaveti; Jon Stewart. ACS symposium series 900, (2005), 366-392.
  7. Effective heterogeneous hydrolysis of phosphodiester by pyridine-containing metallopolymers. Ahmed I. Hanafy, Vasiliki Lykourinou-Tibbs, Kirpal S. Bisht, and Li-June Ming. Inorganica Chimica Acta, 2005, 358(4), 1247-1252.
  8. Synthesis of polyhydroxy cavitands and intramolecular inclusion of their octaester derivatives. Eric Efrain Dueno and Kirpal S. Bisht. Tetrahedron, 2004, 60 (48), 10859-10868.
  9. A chemo-enzymatic synthesis of Imperanene via Enzymatic Asymmetrization of an Intermediary 1,3-diol. Jason Carr and Kirpal S. Bisht. Organic Letters, 2004, 6, 3297-3300.
  10. Intramolecular inclusion in novel octaester cavitands. Eric Dueno and Kirpal S, Bisht. Chemical Communications, 2004, 954-955.
  11. Lipase-catalyzed resolution of racemic substituted ß-Aryl- ß-Lactams. Jason A. Carr, Talal F Al-Azemi, Timothy E. Long, Jeung-Yeop Shim, Cristina A. Coates, Edward E. Turos, and Kirpal S. Bisht. Tetrahedron, 2003, 59, 9147-9160.
  12. Lipase catalyzed Regioselective transesterification in peracylated sophorolipids catalyzed by Candida antarctica lipase-B. Jason A. Carr and Kirpal S. Bisht. Tetrahedron, 2003, 59, 7713-7724.
  13. A MALDI, TGA, TG/MS, and DEA study of the irradiation effects on PMMA. S. R. Tatro, G. R. Baker, Kirpal S. Bisht and J. P. Harmon. Polymer, 2003, 44, 167-176.
  14. Solventless enantioelective ring-opening polymerization of substituted e- caprolactones by enzymatic catalysis. Talal F. Al Azemi, Leelakrishna Kondaveti, and Kirpal S. Bisht. Macromolecules, 2002, 35, 3380-86.
  15. One-step synthesis of polycarbonates bearing pendant functional groups by ring opening polymerization. Talal F. Al Azemi and Kirpal S. Bisht. Journal of Polymer Science-A: Polymer Chemistry , 2002, 40, 1267-1274.
  16. Lipase-catalyzed solvent-free kinetic resolution of substituted racemic e- caprolactones. Leelakrishna Kondaveti, Talal F. Al Azemi, and Kirpal S. Bisht. Tetrahedron Asymmetry, 2002, 13, 129-35.
  17. Functional polycarbonates synthesis: Enzymatic approach. Talal F. Al-Azemi, and Kirpal S. Bisht. In Biocatalysis in Polymer Science, ACS, Washington, DC, (2002), Ch. 14 , 156-171.
  18. Synthesis of novel bis- and tris-(cyclic carbonate)s and their use in preparation of polymer networks. Talal F. Al Azemi and Kirpal S. Bisht. Polymer, 2002, 43, 2161-67.
  19. Novel poly(carbonate) and poly(carbonate-ester) networks. Talal F. Al Azemi and Kirpal S. Bisht. Polymer Prep, 2002, 43(1), 613-614.
  20. Chiral polyesters by in-vitro enzymatic catalysis. Talal F. Al Azemi and Kirpal S. Bisht. Polymer Prep, 2002, 43(1), 704-705.
  21. The synthesis and polymerization of glycolipid-based monomers. Kirpal S. Bisht and Richard A. Gross. In ACS Symposium Series # 786 Biopolymers from Polysaccharides and Agroproteins, American Chemical Society, Washington, D.C., (2001), Ch. 14, 222-239.
  22. Synthesis of novel polycarbonates containing pendant carboxyl groups by enzyme catalysis. Talal F. Al-Azemi, Kirpal S. Bisht. Polymeric Materials: Science and Engineering, 2001, 84, 1045-46.
  23. Enzyme-Catalyzed Ring-Opening Copolymerization of 5-Methyl-5- benzyloxycarbonyl-1,3-dioxan-2-one (MBC) with Trimethylene carbonate (TMC): Synthesis and Characterization. Talal F Al-Azemi, Julie P. Harmon and Kirpal S. Bisht. Biomacromolecules, 2000, 1, 493-500.
  24. Glycolipids from Candida bombicola: Polymerization of a 6-O-acryloyl sophorolipid derivative. Kirpal S. Bisht, Wei Gao and Richard A. Gross. Macromolecules, 2000, 33, 6208-6210.
  25. Functional polycarbonate synthesis: Enzymatic approach. Kirpal S. Bisht and Talal F. Al Azemi. Proc. Am. Chem. Soc.: Polymer Preprints, 2000, 41, 1865-66.