http://www.usf.edu

| Prospective Students | Current Students | Parents | Alumni & Friends | Faculty & Staff | Community | Campuses |

USF Home > Department of Chemistry

Department of Chemistry

Selected Publications

  1. "Discovery of a Novel Shp2 Protein Tyrosine Phosphatase Inhibitor." Chen, L.; Sung, S-S.; Yip, M. L. R.; Lawrence, H. R.; Ren, Y.; Guida, W. C.; Sebti, S. M.; Lawrence, N. J.; Wu, J. Mol. Pharm., 2006, 70, 562.
  2. "Protein Farnesyltransferase: Flexible Docking Studies on Inhibitors Using Computational Modeling", Guida, W. C.; Hamilton, A.D.; Crotty, J.W.; and Sebti, S. M. J. Comp. Aided Mol. Des., 2005, 19, 871.
  3. "IL-8/CXC ligand 8 survives neonatal gastric digestion as a result of intrinsic aspartyl proteinase resistance", Maheshwari A.; Lu, W.; Guida, W. C.; Christensen, R. D.; Calhoun, D. A. Pediatric Res. 2005, 57, 438.
  4. "Copper storage diseases: Menkes, Wilsons, and cancer", Daniel, K. G.; Harbach, R. H.; Guida, W. C.; Dou, Q. P. Front. Biosci. 2004, 9, 2652.
  5. "Organic Copper Complexes as a New Class of Proteasome Inhibitors and Apoptosis Inducers in Human Cancer Cells", Daniel, K. G.; Gupta, P.; Harbach, R. H.; Guida, W. C.; Dou, Q. P. Biochem. Pharm. 2004, 67, 1139.
  6. "Docking Studies and Model Development of Tea Polyphenol Proteasome Inhibitors: Applications to Rational Drug Design", Smith, D. M.; Daniel, K. G.; Wang, Z.; Guida, W. C.; Chan, T-H.; Dou, Q. P. Proteins: Structure Function and Genetics 2004, 54, 58.
  7. "Circular Permutation of 5-Aminolevulinate Synthase", Cheltsov, A. V., Guida, W. C.; Ferreira, G. C. J. Biol. Chem. 2003, 278, 27945.
  8. "Design of Novel N-(2,4-Dioxo-1,2,3,4-tetrahydro-thieno[3,2-d] pyrimidin-7-yl)-guanidines as Thymidine Phosphorylase Inhibitors, and Flexible Docking to a Homology Model", Price, M. L. P.; Guida, W. C.; Jackson, T. E.; Nydick, J. A.; Gladstone, P. L.; Juarez, J. C.; Donate, F.; Ternansky, R. J. Bioorg. Med. Chem. Lett. 2003, 13, 107.
  9. "Chemosensors for the Marine Toxin Saxitoxin", Gawley, R.E; Pinet, S., Cardona, C. M; Probal, D. K; Tong, R.; Guida, W. C.; Nydick, J.; Leblanc, R. M. J. Am. Chem. Soc. 2002, 124, 13448.
  10. "Accurate Prediction of the Acidity Constant by ab-initio Methods", Klicic, J. A.; Friesner, R. A.; Liu, S-Y.; Guida, W. C. J. Phys. Chem. 2002, 106, 1327.
  11. "Low-mode Conformational Search Elucidated. Application to C39H80 and Flexible Docking of 9-Deazaguanine Inhibitors to PNP" Kolossvary, I.; Guida, W. C. J. Comp. Chem. 1999, 20, 1671.
  12. "Purine Nucleoside Phosphorylase. Catalytic Mechanism" Erion, M. D.; Stoeckler, J. D.; Guida, W. C.; Walter, R. L.; Ealick, S. E. Biochemistry 1997, 36,11735.
  13. "Low Mode Search. An Efficient, Automated Computational Method for Conformational Analysis: Application to Cyclic and Acyclic Alkanes and Cyclic Peptides" Kolossvary, I.; Guida, W. C. J . Am. Chem. Soc. 1996, 118, 5011.
  14. "The Art and Practice of Structure-Based Drug Design: A Molecular Modeling Perspective" Bohacek, R. S.; McMartin, C.; Guida, W. C. Medicinal Research Reviews, 1996, 16, 3.