banner USF Home College of Arts & Sciences OASIS myUSF USF A-Z Index

USF Home > College of Arts and Sciences > Chemistry Department

Roman  Manetsch

Roman Manetsch

Roman Manetsch
Courtesy Professor

Contact

Office:
Phone:
Email:

Links

Personal Bio

fiogf49gjkf0d

Education

Diploma in Chemistry, University of Basel (Switzerland), 1998
Ph.D., University of Basel (Switzerland), 2002
Postdoctoral Fellow, The Scripps Research Institute (La Jolla, CA), 2002-2005

Specialty Area

fiogf49gjkf0d

Recent Journal Articles

fiogf49gjkf0d

Honors and Award

fiogf49gjkf0d

Books

fiogf49gjkf0d

Presentations

fiogf49gjkf0d

Recent Publications

fiogf49gjkf0d
  1. Nacheva K P, Maza W, Mayer D Z, Fronczek F, Larsen R W, Manetsch R*. Fluorescent Properties and Resonance Energy Transfer of 3,4-bis(2,4-difluorophenyl)-maleimide. Submitted.
  2. Kumar A B, Anderson J M, Melendez A L, Manetsch R*. Synthesis and structure-activity relationship studies of 1,3-disubstituted 2-propanols as BACE-1 inhibitors. Submitted.
  3. Namelikonda N K, Manetsch R*. Sulfo-click reaction via in situ generated thioacids and its application in kinetic target-guided synthesis. Chem Commun 2012; 48, 1526-1528.
    Article has been published in the "Emerging Investigators 2012" issue.
  4. Cross R M, Namelikonda N K, Mutka T S, Luong L, Kyle D E, Manetsch R*. Synthesis, Antimalarial Activity, and Structure–Activity Relationship of 7-(2-Phenoxyethoxy)-4(1H)-quinolones. J Med Chem 2011; 54, 8321-8327.
  5. Kumar A B, Anderson J, Manetsch, R*. Design, Synthesis and Photoactivation Studies of Fluorous Photolabels. Org Biomol Chem 2011; 9, 6284-6292.
  6. Kulkarni S S, Hu X-D, Doi K, Wang H-G, Manetsch R*. Screening of Protein-Protein Interaction Modulators via Sulfo-Click Kinetic Target-Guided Synthesis. ACS Chemical Biology 2011; 6, 724-732.
    Appeared in the list of 20 "most read" ACS Chemical Biology articles in 2011.
  7. Cross M R, Maignan J R, Mutka T S, Luong L, Sargent J, Kyle D K, Manetsch R*. Optimization of 1,2,3,4-Tetrahydroacridin-9(10H)-ones as Antimalarials Utilizing Structure-Activity and Structure-Property Relationships. J Med Chem 2011; 54, 4399-4426.
  8. Cross R M, Manetsch R*. Divergent Route to Access Structurally Diverse 4-Quinolones via Mono or Sequential Cross-Couplings. J Org Chem 2010; 75, 8654-8657.
  9. Cross M R, Monastyrskyi A, Mutka T S, Burrows J, Kyle D K, Manetsch R*. Endochin Optimization: Structure-Activity and Structure-Property Relationship Studies of 3-substituted 2-Methyl-3(1H)-quinolones with Antimalarial Activity. J Med Chem 2010; 53, 7076-7094.
  10. Hu. X. Manetsch R*. Kinetic Target-Guided Synthesis. Chem Soc Rev 2010, 39, 1316-1324.
  11. Radic Z, Manetsch R, Fournier D, Sharpless KB, Taylor P*. Probing Gorge Dimensions of Cholinesterases by Freeze-Frame Click Chemistry. Chem-Biol Interact 2008; 175: 161-165.
  12. Hu X, Sun J, Wang H-G, Manetsch R*. Bcl-XL-Templated Assembly of its Own Protein-Protein Interaction Modulator from Fragments Decorated with Thio Acids and Sulfonyl Azides. J Am Chem Soc 2008; 130: 13820-13821.
  13. Sharpless KB, Manetsch R*. In Situ Click Chemistry: A Powerful Means for Lead Discovery (Review). Expert Opinion on Drug Discovery 2006; 1: 525-538.