Department of Chemistry

Mark L. McLaughlin

Mark L. McLaughlin
Professor of Chemistry and Interdisciplinary Oncology

Contact Information

Department of Chemistry
University of South Florida
4202 E. Fowler Avenue, CHE 205A
Tampa, FL 33620-5250

Office: (813) 974-0014, NES 405A
Lab: (813) 974-7365, NES 405
Email: mmclaugh@cas.usf.edu

Education

B.S. in Chemistry, Christian Brothers College, Memphis, TN, 1979
Ph.D. in Organic Chemistry, Georgia Institute of Technology, 1983
Dissertation: Synthesis and Reactions of Aroylphosphides and Lewis Acid Catalyzed Aldol Condensations
Advisor: Charles L. Liotta
Postdoctoral Research -
Physical Organic Chemistry, Rice University, 1983-85
Mentor: Edward S. Lewis
Postdoctoral Research -
Synthetic Organic Chemistry, The Ohio State University, 1985-86
Mentor: Leo A. Paquette

Research Areas

We are investigating: short highly helical amphipathic peptides with direct and indirect antimicrobial activity and anticancer activity and constrained dipeptides that enforce an extended conformation for use in the synthesis of stable beta-sheet-like peptide structures with applications to age-related disease such as Alzheimer's and Parkinson's disease. We are developing a new class of HIV protease inhibitors based on easily synthesized constrained dipeptide-like units using a structure-based approach.

Graduate Researchers

David Badger, Priyesh Jain, Sridhar Kaulagari, Philip Murray, Melissa Topper, Mingzhou Zhou

Current Courses (Fall 2009)

REF	PRX CRS	SEC	Course Title	CR	Day	Time	Bldg	Room
85188	CHM 2211	901	Organic Chemistry II M 7:35pm-9:45pm scheduled exam time You can register in organic II lecture w/out the lab	3	T TR M	3:30pm-4:20pm 5:00pm-6:15pm 7:35pm-9:45pm	LIF CHE CHE	269 111 111
85189	CHM 2211	902	Organic Chemistry II M 7:35pm-9:45pm scheduled exam time You can register in organic II lecture without the lab but	3	M T TR	7:35pm-9:45pm 3:30pm-4:20pm 5:00pm-6:15pm	CHE CHE CHE	111 101A 111
85191	CHM 2211	903	Organic Chemistry II M 7:35pm-9:45pm, scheduled exam time. You can register in organic II lecture w/out the lab,	3	M R TR	7:35pm-9:45pm 3:30pm-4:20pm 5:00pm-6:15pm	CHE LIF CHE	111 269 111
85192	CHM 2211	904	Organic Chemistry II M 7:35-9:45pm, scheduled exam time. You can register in organic II lecture w/out the lab,	3	M R TR	7:35pm-9:45pm 3:30pm-4:20pm 5:00pm-6:15pm	CHE CHE CHE	111 303 111
89325	CHM 2211	905	Organic Chemistry II M 7:35pm-9:45pm, scheduled exam time. You can register in organic II lecture w/out the lab,	3	TR T M	5:00pm-6:15pm 2:00pm-2:50pm 7:35pm-9:45pm	CHE CIS CHE	111 1023 100
89326	CHM 2211	906	Organic Chemistry II M 7:35pm-9:45pm, scheduled exam time. You can register in organic II lecture w/out the lab,	3	TR R M	5:00pm-6:15pm 2:00pm-2:50pm 7:35pm-9:45pm	CHE CPR CHE	111 480 100