Department of Chemistry

Mark L. McLaughlin

Mark L. McLaughlin
Professor of Chemistry and Interdisciplinary Oncology

Contact Information

Department of Chemistry
University of South Florida
4202 E. Fowler Avenue, CHE 205A
Tampa, FL 33620-5250

Office: (813) 974-0014, NES 405A
Lab: (813) 974-7365, NES 405
Email: mmclaugh@cas.usf.edu

Education

B.S. in Chemistry, Christian Brothers College, Memphis, TN, 1979
Ph.D. in Organic Chemistry, Georgia Institute of Technology, 1983
Dissertation: Synthesis and Reactions of Aroylphosphides and Lewis Acid Catalyzed Aldol Condensations
Advisor: Charles L. Liotta
Postdoctoral Research -
Physical Organic Chemistry, Rice University, 1983-85
Mentor: Edward S. Lewis
Postdoctoral Research -
Synthetic Organic Chemistry, The Ohio State University, 1985-86
Mentor: Leo A. Paquette

Research Areas

We are investigating: short highly helical amphipathic peptides with direct and indirect antimicrobial activity and anticancer activity and constrained dipeptides that enforce an extended conformation for use in the synthesis of stable beta-sheet-like peptide structures with applications to age-related disease such as Alzheimer's and Parkinson's disease. We are developing a new class of HIV protease inhibitors based on easily synthesized constrained dipeptide-like units using a structure-based approach.

Graduate Researchers

Mehul Ajmera, Laura Anderson, David Badger, Priyesh Jain, Philip Murray, Melissa Topper, Sung Wook Yi, Mingzhou Zhou

Current Courses (Fall 2008)

REF	PRX CRS	SEC	Course Title	CR	Day	Time	Bldg	Room
81829	CHM 2211	001	Organic Chemistry II M 5:15pm-6:05pm, scheduled exam time. You can register in organic II lecture w/out the lab,	3	M T TR	5:15pm-6:05pm 2:00pm-2:50pm 11:00am-12:15pm	ENA EDU CHE	105 411 111
81830	CHM 2211	002	Organic Chemistry II M 5:15pm-6:05pm, scheduled exam time. You can register in organic II lecture w/out the lab,	3	M R TR	5:15pm-6:05pm 2:00pm-2:50pm 11:00am-12:15pm	ENA CPR CHE	105 480 111
81831	CHM 2211	003	Organic Chemistry II M 5:15pm-6:05pm, scheduled exam time. You can register in organic II lecture w/out the lab,	3	M T TR	5:15pm-6:05pm 12:30pm-1:20pm 11:00am-12:15pm	ENA CPR CHE	105 205 111
81832	CHM 2211	004	Organic Chemistry II M 5:15pm-6:05pm, scheduled exam time. You can register in organic II lecture w/out the lab,	3	M R TR	5:15pm-6:05pm 12:30pm-1:20pm 11:00am-12:15pm	ENA LIF CHE	105 261 111