Department of Chemistry

H. Lee Woodcock

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H. Lee Woodcock
Assistant Professor

Contact Information

Department of Chemistry
University of South Florida
4202 E. Fowler Avenue, CHE 205A
Tampa, FL 33620-5250

Office: (813) 974-9239, CHE 206A
Lab: CHE 206
Email: hlw@mail.usf.edu

Education

B.S., Appalachian State University, 1998
Ph.D., University of Georgia, 2003
Lenfant Biomedical Fellow (National Heart, Lung, and Blood Institute, NIH), 2008
Career Transition Award (K22, National Heart, Lung, and Blood Institute, NIH), 2009

Research Areas

Computational Chemistry / Biophysical Chemistry

The research in our lab focuses on the development and application of molecular simulation techniques to solve interesting problems that exist at the interface of chemistry, biology and medicine. I currently have two main areas of interest:

1. Examination of structure, dynamics, and mechanism by simulation. Specifically, this focuses on two main areas; examination of antibiotic and inhibitor resistance mechanisms with hybrid quantum mechanical and molecular mechanical (QM/MM) methods and elucidation of carbohydrate structure and dynamics as related to energy production.
2. Development of new simulation and analysis techniques. This area primarily focuses on multi-scale modeling methods, techniques for computing free energies of enzymatically catalyzed reactions, and methods for probing the normal modes of complex systems.

Current Courses (Fall 2009)