| Acevedo-Duncan |
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Investigates signal transduction pathways involved in cell cycle control in high-grade gliomas, one of the most radioresistant forms of cancer for which there is no
current successful therapy... |
| Antilla |
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Chiral Organocatalysis, Metal-Catalysis, New Stereoselective Reaction Methodology, Drug Discovery... |
| Baker |
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Natural product isolation and characterization from marine invertebrates, biosynthesis and synthesis of secondary metabolites from marine invertebrates, chemical ecology... |
| Bisht |
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Efficient and environmentally friendly synthetic routes towards synthesis of polymers for biodegradable applications, stereo-controlled synthesis/modification of molecules
that serve as precursors to biologically active molecules... |
| Cai |
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Design of small molecules mimicking EGF and EGFR as potential anti-cancer agents, design of novel non-natural peptidomimetics mimicking bioactive peptides,
development of activity based probes (ABP) and inhibitors for BACE- Alzheimer's disease β-secretase enzyme... |
| Guida |
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Computer aided drug design, design of inhibitors of enzymes essential for the biosynthesis of polyamines, design of inhibitors of protein-protein interactions
that have therapeutic relevance in cancer, development of enhanced methods for the docking of inhibitors into protein binding sites... |
| Manetsch |
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The research interests represent a well-balanced blend of organic and biological chemistry, addressing in particular modern aspects of medicinal chemistry.
The conducted research includes development of new drug/target discovery methods and organic synthesis of new biochemical tools, as well as their application
to biologically relevant processes... |
| McLaughlin |
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We are investigating short highly helical amphipathic peptides with direct and indirect antimicrobial activity and anticancer activity and constrained dipeptides
for use in the synthesis of stable beta-sheet-like peptide structures with applications to diseases such as Alzheimer's and Parkinson's disease. We are developing
a new class of HIV protease inhibitors... |
| Merkler |
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Post-translational, C-terminal amidation is required for the full biological activity of most mammalian peptide hormones. The research in my laboratory has involved
the basic characterization of peptidylglycine a-amidating enzyme (PAM).... |
| Turos |
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Our research group is focusing on the synthesis and evaluation of new antibacterial and anticancer agents, as well as development of nanoparticle polymers as drug
delivery vehicles and biomedical plastics... |
| Zhang |
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The primary research interests of our group are in the areas of organic and organometallic chemistry. The research program involves the design and synthesis of
new organic and organometallic compounds, and the exploration of their applications in the areas of catalysis, materials, and medicine... |